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Introduction
Mannitol is a hexanol, which is more widely used in the manufacture of chewable tablets such as sobriety medicine and mouth coolant because it absorbs heat when dissolved, has a sweet taste, and has a comfortable sensation to the mouth, and its granular form is specially used as an excipient for direct compression tablets. Mannitol is a kind of hypertonic tissue dehydrating agent, which is widely used clinically in the treatment of cerebral edema, the prevention of acute renal failure, the treatment of glaucoma, and the acceleration of the excretion of poisons and drugs from the kidneys.
Formula: C6H14O6
Molecular Formula: 182.17
Molecular Weight: 182.17 CAS No.: 69-65-8
EINECS No.: 201-770-2;200-711-8
Item No :
69-65-8Order(MOQ) :
1000kgsPayment :
T/T;LC;CREDIT PAYMENTProduct Origin :
ChinaColor :
Light Beige or Milky White PowderShipping Port :
Main Port,ChinaLead Time :
All The Way AroundWeight :
25KG/BAGSpecification
Specification
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Physical Controls
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White powder
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Characteristics
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Characteristic
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100 Hundred million CFU/G
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≤5.0%
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≤5.0%
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95% Pass through 80 points
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No
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Chemical control
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NMT 10ppm
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NMT 2ppm
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NMT 2ppm
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NMT 2ppm
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NMT 2ppm
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No genetically modified organisms
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Microbial control
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The largest 10,000cfu/g
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The largest 1,000cfu/g
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Negative
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Applications
Mannitol in medicine is a good diuretic, reduce intracranial pressure, intraocular pressure and treatment of renal drugs, dehydrating agents, sugar substitutes, also used as excipient of tablets and solid, liquid diluent. Mannitol Injection, as a high osmotic hypotensive drug, is a commonly used drug for clinical rescue, especially for brain diseases, with the characteristics of fast pressure reduction and accurate efficacy required for drugs to reduce intracranial pressure. As an excipient for tablets, mannitol is non-hygroscopic, fast drying, good chemical stability, and has the characteristics of crispness, good granulation, etc. It is used in most of the tablets such as anticancer drugs, antibacterial drugs, antihistamines and vitamins. In addition, it is also used in chewable tablets such as sobriety medicine and mouth coolant. In terms of food, the product in the sugar and sugar alcohols in the minimum water absorption, and has a refreshing sweetness, used for maltose, chewing gum, rice cakes and other food products such as anti-adhesion, as well as used as a general confectionery anti-adhesion powder. Can also be used as food for diabetics, bodybuilding food and other low calorie, low sugar sweetener. In industry, mannitol can be used in the plastics industry, the production of rosin acid ester and margarine resin, explosives, detonators (nitro-mannitol) and so on. In chemical analysis for the determination of boron, biological testing used as a bacterial culture agent. Mannitol can be absorbed by the human stomach and intestines, but does not accumulate in the body. After being absorbed, part of it is metabolized in the body, and the other part is discharged from the urine; dibromomannitol can be produced by hydrobromic acid reaction.
Used in the synthesis of resins and medicines; dehydration drugs, diuretics. Treatment of cerebral edema and glaucoma, acute oliguria, prevention of acute renal failure, treatment of nephrotic syndrome edema. Active intracranial hemorrhage is prohibited injection (except craniotomy).
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