Q1: What is Pharmaceutical Grade Silicon Dioxide CAS 7631-86-9?
A: Pharmaceutical Grade Silicon Dioxide is a high-purity amorphous colloidal silica with CAS 7631-86-9. It is a safe pharmaceutical excipient and antioxidant stabilizer, fully compliant with USP, EP, BP and FDA pharmacopoeia standards, widely used in pharmaceutical and healthcare formulations.
Q2: What are the main functions of pharmaceutical grade silicon dioxide?
A: It acts as antioxidant stabilizer, glidant, anti-caking agent, flow aid and adsorbent. It prevents ingredient oxidation and moisture agglomeration, improves powder fluidity, stabilizes formulation performance and extends drug shelf life.
Q3: What pharmaceutical products can silicon dioxide be used in?
A: It is widely applied in tablets, capsules, granules, powder medicines, oral suspensions, ointments, vitamin supplements and probiotic healthcare products.
Q4: Is pharmaceutical grade silicon dioxide safe for human ingestion?
A: Yes. It is chemically inert, non-toxic, non-irritating and free of harmful residues. It meets global pharmaceutical safety standards and is approved as a safe oral pharmaceutical excipient.
Q5: What is the difference between pharmaceutical grade and industrial grade silicon dioxide?
A: Pharmaceutical grade silica adopts GMP purification production, with ultra-low heavy metal and impurity content, complying with strict pharmacopoeia standards. Industrial grade has loose impurity control and cannot be used for drugs and health products.
Q6: What is the standard purity and particle size of your pharma-grade SiO2?
A: Our pharmaceutical grade silicon dioxide purity reaches ≥99.5%, with particle size 7–40 nm and high specific surface area, ensuring stable adsorption and excellent flow-aiding performance.
Q7: Does silicon dioxide affect drug efficacy or dissolution speed?
A: Under standard dosage, it will not affect drug dissolution, disintegration or efficacy. It only optimizes physical properties of the formulation without chemical reaction with active ingredients.
Q8: What is the recommended dosage in pharmaceutical formulations?
A: The general dosage ranges from 0.1% to 2.0% according to different formulas. It is recommended to conduct small-scale formulation tests before mass production.
Q9: Can pharmaceutical silicon dioxide be mixed with other excipients?
A: Yes. It features excellent compatibility with most fillers, binders, stabilizers and emulsifiers, helping improve overall formulation stability and product uniformity.
Q10: What is the shelf life and storage requirement?
A: The shelf life is 24 months. Store in cool, dry, ventilated and sealed conditions, avoid moisture, high temperature and direct sunlight to prevent agglomeration.
Q11: Can you provide free samples and technical support?
A: Yes, we support free samples for customer formula testing. We also provide professional formulation guidance and technical after-sales service.
Q12: What export documents and certificates can you provide? A: We can provide complete COA, MSDS, DMF reference documents,food & pharmaceutical safety
certificates, health certificates and customs clearance documents to meet global import registration
requirements.
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